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Why is inflammation so important in the lung?
Because the lung is constantly exposed to harmful pathogens, an immediate and intense defense action (mainly inflammation) is required to eliminate the invaders as early as possible. A delicate balance between inflammation and anti-inflammation is essential for lung homeostasis.
How are inflammatory cells activated in the body?
During inflammation, numerous types of inflammatory cells are activated. Each releases cytokines and mediators to modify activities of other inflammatory cells. Orchestration of these cells and molecules leads to progression of inflammation.
How is the inflammatory response related to ischemia?
The inflammatory pathways in this particular model are very similar to events related to lung injury caused by ischemia, 3 by the presence of bacteria, 4 or by bacterial lipopolysaccharide. 5 These events trigger complement activation as well as activation of tissue macrophages.
Which is an example of an inflammatory response?
Inflammation is the body’s response to insults, which include infection, trauma, and hypersensitivity. The inflammatory response is complex and involves a variety of mechanisms to defend against pathogens and repair tissue. In the lung, inflammation is usually caused by pathogens or by exposure to toxins, pollutants, irritants, and allergens.
Last Update: Oct 2021
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