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How is mass spectrometry used to weigh molecules?
Mass spectrometry is essentially a technique for "weighing" molecules. Obviously, this* is not done with a conventional balance or scale. Instead, mass spectrometry is based upon the motion of a charged particle, called an ion, in an electric or magnetic field. The mass to charge ratio (m/z) of the ion effects this motion.
How are mass spectrometers used in everyday life?
The early mass spectrometers were primarily used by physicists to study the atomic weight of the elements and the natural relative abundance of elemental isotopes [ 1 ]. Although these early instruments could not be used to study biomolecules, it was not long before they were used to study heavy isotopes as tracers in biological systems [ 3 ].
When was mass spectrometry first used in biological research?
Time-of-flight (TOF) mass analysis had been developed and commercialized by 1956, but relatively poor mass resolution was a problem until improvements were made in the early 1970s [ 13 ]. An ionization technique for biological molecules that could be used with TOF analysis was introduced in 1991.
Where can I find the instructions for a spectrometer?
Instructions for your spectrometer can be printed or viewed on this letter-sized PDF pattern which should also come included in your kit. You can also follow along with these instructions: Cut out along the outer edge if not already cut out. Fold as indicated by the lines.
Last Update: Oct 2021
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